Research Article
Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats
Table 1
Pharmacokinetic parameters of baicalin after intravenous administration in rats.
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Once daily for 7 days. Rats received intravenous administration of baicalin at a single dose of 0.225 or 0.45 g/kg () or at a dose of 0.90 g/kg once for 1 day and the same dose for 7 days . The results were means SD of the indicated number of rats. |