Research Article

An Aqueous-Ethanol Extract of Liriope spicata var. prolifera Ameliorates Diabetic Nephropathy through Suppression of Renal Inflammation

Figure 1

(a) Representative photomicrographs (original magnification, 400x) of PAS-stained kidney sections from STZ-diabetic rats treated for eight weeks with TRLS-ext. STZ-diabetic rats were dosed by oral gavage once daily for eight weeks with 100 mg kg−1 TRLS-ext (STZ + TRLS 100) or 200 mg kg−1 TRLS-ext (STZ + TRLS 200). Normal (normal + vehicle) or STZ-diabetic rats receiving vehicle treatment (STZ + vehicle) were administered the same volume of vehicle (distilled water) used to disperse TRLS-ext. (b) Results of quantification of the glomerulosclerosis index. (c) Score for tubulointerstitial lesions for each group. Values (mean ± SD) were obtained for each group of 4 animals. compared to vehicle-treated normal rats. and compared to vehicle-treated STZ-diabetic rats, respectively.
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