Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 217198, 10 pages
http://dx.doi.org/10.1155/2013/217198
Research Article

Evaluation of Therapeutic Intervention with a Natural Product in Cutaneous Wound Healing: The Use of Capybara Oil

Laboratory of Ultrastructure and Tecidual Biology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551-030 Rio de Janeiro, RJ, Brazil

Received 16 February 2013; Accepted 19 May 2013

Academic Editor: Carlo Ventura

Copyright © 2013 Polyana Cury Marinho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Li, J. Chen, and R. Kirsner, “Pathophysiology of acute wound healing,” Clinics in Dermatology, vol. 25, no. 1, pp. 9–18, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Ghaderi, M. Afshar, H. Akhbarie, and M. J. Golalipour, “Comparison of the efficacy of honey and animal oil in accelerating healing of full thickness wound of mice skin,” International Journal of Morphology, vol. 28, no. 1, pp. 193–198, 2010. View at Google Scholar · View at Scopus
  3. B. S. Nayak, J. Kanhai, D. M. Milne, L. P. Pereira, and W. H. Swanston, “Experimental evaluation of ethanolic extract of carapa guianensis L. leaf for its wound healing activity using three wound models,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 419612, 6 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. L. M. L. Parente, R. D. S. Lino Júnior, L. M. F. Tresvenzol, M. C. Vinaud, J. R. De Paula, and N. M. Paulo, “Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 375671, 7 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. L. E. Rojo, C. M. Villano, G. Joseph et al., “Wound-healing properties of nut oil from Pouteria lucuma,” Journal of Cosmetic Dermatology, vol. 9, no. 3, pp. 185–195, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. L. H. Terkelsen, A. Eskild-Jensen, H. Kjeldsen, J. H. Barker, and V. E. Hjortdal, “Topical application of cod liver oil ointment accelerates wound healing: an experimental study in wounds in the ears of hairless mice,” Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, vol. 34, no. 1, pp. 15–20, 2000. View at Google Scholar · View at Scopus
  7. X.-W. Qiu, J.-H. Wang, X.-W. Fang, Z.-Y. Gong, Z.-Q. Li, and Z.-H. Yi, “Anti-inflammatory activity and healing-promoting effects of topical application of emu oil on wound in scalded rats,” Di Yi Jun Yi Da Xue Xue Bao, vol. 25, no. 4, pp. 407–410, 2005. View at Google Scholar · View at Scopus
  8. H.-L. Li, L.-P. Chen, Y.-H. Hu et al., “Crocodile oil enhances cutaneous burn wound healing and reduces scar formation in rats,” Academic Emergency Medicine, vol. 19, no. 3, pp. 265–273, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. E. Hatanaka and R. Curi, “Ácidos graxos e cicatrização: uma revisão,” Revista Brasileira de Farmacognosia, vol. 88, no. 2, pp. 53–58, 2007. View at Google Scholar
  10. L. M. Pereira, E. Hatanaka, E. F. Martins et al., “Effect of oleic and linoleic acids on the inflammatory phase of wound healing in rats,” Cell Biochemistry and Function, vol. 26, no. 2, pp. 197–204, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Federico and G. A. Canziani, “Modeling the population dynamics of capybara Hydrochaeris hydrochaeris: a first step towards a management plan,” Ecological Modelling, vol. 186, no. 1, pp. 111–121, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Fukushima, Y. Takayama, T. Habaguchi, and M. Nakano, “Comparative hypocholesterolemic effects of capybara (Hydrochoerus hydrochaeris dabbenei) oil, horse oil, and sardine oil in cholesterol-fed rats,” Lipids, vol. 32, no. 4, pp. 391–395, 1997. View at Publisher · View at Google Scholar · View at Scopus
  13. M. S. Pinheiro, J. J. C. Silva, and R. C. Rodrigues, “Utilização sustentável e domesticação da capivara,” Circular Técnica Da Embrapa Clima Temperado, vol. 31, pp. 1–68, 2001. View at Google Scholar
  14. M. S. Pinheiro, “A criação em sistema semi-intensivo e o manejo sustentável de capivaras na natureza,” Documentos Da Embrapa Clima Temperado, vol. 232, pp. 1–36, 2008. View at Google Scholar
  15. C. A. Mandarim-de-Lacerda, “Stereological tools in biomedical research,” Anais da Academia Brasileira de Ciencias, vol. 75, no. 4, pp. 469–486, 2003. View at Google Scholar · View at Scopus
  16. B. Romana-Souza, J. S. Santos, and A. Monte-Alto-Costa, “β-1 and β-2, but not α-1 and α-2, adrenoceptor blockade delays rat cutaneous wound healing,” Wound Repair and Regeneration, vol. 17, no. 2, pp. 230–239, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Kietzmann, “Improvement and retardation of wound healing: effects of pharmacological agents in laboratory animal studies,” Veterinary Dermatology, vol. 10, no. 2, pp. 83–88, 1999. View at Google Scholar · View at Scopus
  18. W. K. Stadelmann, A. G. Digenis, and G. R. Tobin, “Physiology and healing dynamics of chronic cutaneous wounds,” American Journal of Surgery, vol. 176, no. 2, pp. 26–38, 1998. View at Publisher · View at Google Scholar · View at Scopus
  19. C. R. B. Cardoso, M. A. Souza, E. A. V. Ferro, S. Favoreto Jr., and J. D. O. Pena, “Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds,” Wound Repair and Regeneration, vol. 12, no. 2, pp. 235–243, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. A. Paulino Do Nascimento and A. Monte-Alto-Costa, “Both obesity-prone and obesity-resistant rats present delayed cutaneous wound healing,” British Journal of Nutrition, vol. 106, no. 4, pp. 603–611, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. R. F. Diegelmann and M. C. Evans, “Wound healing: an overview of acute, fibrotic and delayed healing,” Frontiers in Bioscience, vol. 9, pp. 283–289, 2004. View at Google Scholar · View at Scopus
  22. B. Romana-Souza, A. P. Nascimento, and A. Monte-Alto-Costa, “Propranolol improves cutaneous wound healing in streptozotocin-induced diabetic rats,” European Journal of Pharmacology, vol. 611, no. 1–3, pp. 77–84, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. P. R. Barroso, R. Lopes-Rocha, E. M. F. Pereira et al., “Effect of propolis on mast cells in wound healing,” Inflammopharmacology, vol. 20, pp. 289–294, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. B. R. Souza, J. S. Santos, and A. M. A. Costa, “Blockade of β1- and β2-adrenoceptors delays wound contraction and re-epithelialization in rats,” Clinical and Experimental Pharmacology and Physiology, vol. 33, no. 5-6, pp. 421–430, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Ebihara, T. Funaki, A. Murakami, S. Takai, and M. Miyazaki, “Mast cell chymase decreases the barrier function and inhibits the migration of corneal epithelial cells,” Current Eye Research, vol. 30, no. 12, pp. 1061–1069, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. J. F. Cardoso, B. R. Souza, T. P. Amadeu, S. S. Valença, L. C. M. S. Porto, and A. M. A. Costa, “Effects of cigarette smoke in mice wound healing is strain dependent,” Toxicologic Pathology, vol. 35, no. 7, pp. 890–896, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. A. P. Nascimento and A. M. A. Costa, “Overweight induced by high-fat diet delays rat cutaneous wound healing,” British Journal of Nutrition, vol. 96, no. 6, pp. 1069–1077, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. B. Romana-Souza and A. Monte-Alto-Costa, “Simultaneous blockade of alpha and beta adrenoceptors impairs cutaneous wound healing in rats,” Journal of the European Academy of Dermatology and Venereology, vol. 24, no. 3, pp. 349–352, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. C. Frantz, K. M. Stewart, and V. M. Weaver, “The extracellular matrix at a glance,” Journal of Cell Science, vol. 123, no. 24, pp. 4195–4200, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. K. E. Kadler, C. Baldock, J. Bella, and R. P. Boot-Handford, “Collagens at a glance,” Journal of Cell Science, vol. 120, no. 12, pp. 1955–1958, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. T. Ushiki, “Collagen fibers, reticular fibers and elastic fibers. A comprehensive understanding from a morphological viewpoint,” Archives of Histology and Cytology, vol. 65, no. 2, pp. 109–126, 2002. View at Google Scholar · View at Scopus
  32. V. N. Rocha, R. Neto-Ferreira, C. A. Mandarim de-Lacerda, and J. J. de Carvalho, “The microfibril-elastin fiber system distribution in left atrioventricular valve of the rat,” International Journal of Morphology, vol. 29, no. 3, pp. 907–913, 2011. View at Google Scholar · View at Scopus
  33. C. M. Kielty, M. J. Sherratt, and C. A. Shuttleworth, “Elastic fibres,” Journal of Cell Science, vol. 115, no. 14, pp. 2817–2828, 2002. View at Google Scholar · View at Scopus
  34. G. Cotta Pereira, F. G. Rodrigo, and S. Bittencourt Sampaio, “Oxytalan, elaunin, and elastic fibers in the human skin,” Journal of Investigative Dermatology, vol. 66, no. 3, pp. 143–148, 1976. View at Google Scholar · View at Scopus
  35. T. P. Amadeu, A. S. Braune, L. C. Porto, A. Desmoulière, and A. M. A. Costa, “Fibrillin-1 and elastin are differentially expressed in hypertrophic scars and keloids,” Wound Repair and Regeneration, vol. 12, no. 2, pp. 169–174, 2004. View at Publisher · View at Google Scholar · View at Scopus