ZHENG-Omics Application in ZHENG Classification and Treatment: Chinese Personalized Medicine
Figure 2
The reversion maps reveal the therapeutic effects of two TCM ZHENG types in hepatitis-B-caused cirrhosis. (a) and (b) Histogram of the therapeutic effects of FZHY Tablet for liver-gallbladder dampness-heat syndrome and liver-kidney Yin deficiency syndrome, respectively, by the changing trend of significantly differential metabolites and classic symptoms. Blue, red, and green bars stand for control group, before intervention and 12-week intervention of FZHY tablet. The -axis represents the changed metabolites and symptoms, and the -axis is fold change of mean ranks calculated by the Mann-Whitney test, compared with the control group. (c) and (d) Curve diagram of regression trend of significantly differential metabolites and classic symptoms in liver-gallbladder dampness-heat syndrome and liver-kidney Yin deficiency syndrome respectively, for 12-week intervention of FZHY tablet. The -axis represents the changed metabolites and symptoms, and the -axis is the rate of reversion, representing the therapeutic effect of FZHY tablet for different ZHENGs.
