Bioinformatics Analysis for the Antirheumatic Effects of Huang-Lian-Jie-Du-Tang from a Network Perspective

Table 1

KEGG pathways significantly enriched with targets of HLJDT’s components.

Pathway class	Pathway name	Total genes; on pathway	HLJDT’s targets; on pathway
Cell communication	Focal adhesion	200	14
Cell growth and death	p53 signaling pathway	69	13
	Apoptosis	86	14
Development	Osteoclast differentiation	128	13
Immune system	Toll-like receptor signaling pathway	102	13
	T-cell receptor signaling pathway	108	13
	NOD-like receptor signaling pathway	59	9
	B-cell receptor signaling pathway	75	9
	Chemokine signaling pathway	189	11
Nervous system	Neurotrophin signaling pathway	127	12
Signal transduction	VEGF signaling pathway	76	10
	MAPK signaling pathway	272	15
Signaling molecules and interaction	Cytokine-cytokine receptor interaction	275	15