In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria

Figure 3

Representative photomicrograph shows morphological changes of selected cancer cells (MCF-7, Ca Ski, and HCT-116). Cells were treated with alismol for 48 h and imaged by inverted phase contrast microscope (magnification 200x). Arrows show (1) control cell, (2) condensed nuclei, (3) cell shrinkage, (4) membrane blebbing, (5) apoptotic bodies, (6) blistering, (7) echinoid spikes, and (8) pyknotic body.