In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria

Table 4

Percentage of necrotic cells (%).

Cell lines	Compounds	12.5 μg/mL	25 μg/mL	40 μg/mL	50 μg/mL
MCF-7	Curzerenone	2.00 ± 1.30^a	3.83 ± 0.60^b	5.50 ± 1.30^c	17.83 ± 2.60^d
	Alismol	3.83 ± 0.30^a	5.17 ± 1.50^b	38.33 ± 1.30^c	58.97 ± 1.10^d
Ca Ski	Curzerenone	3.50 ± 1.30^a	5.57 ± 1.10^b	11.83 ± 2.10^c	16.33 ± 1.0^d
	Alismol	5.83 ± 1.50^a	14.00 ± 3.50^b	45.33 ± 0.60^c	60.33 ± 1.00^d
HCT-116	Curzerenone	9.00 ± 1.50^a	15.33 ± 0.80^b	25.00 ± 0.50^c	28.00 ± 0.50^d
	Alismol	19.50 ± 1.00^a	26.00 ± 1.30^b	67.67 ± 2.60^c	76.67 ± 0.80^d

Values expressed are mean ± standard deviation (SD) of triplicate measurements. For the compounds with the different concentration, means in the same rows with different letters (a–d) were significantly different (𝑃<0.05).