The Effects of Acupuncture on Bladder Interstitial Cells of Cajal Excitability in Rats with Overactive Bladder

Figure 6

Changes of distribution and quantity in bladder ICCs. ((a), (b), (c), and (d)) Immunofluorescence of c-Kit in bladder. Nucleus stained by DAPI (blue), c-Kit (red) in urothelium, suburothelia, and muscle layer. c-Kit-positive ICCs (↑). (a) Normal control group, (b) model group, (c) acupuncture group, and (d) Glivec group. Scale bar is 50 μm. (e) Comparisons of relative quantity of ICCs in bladder after treatment. * versus normal control group 𝑃<0.05.

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