Tetrandrine Suppresses Cancer Angiogenesis and Metastasis in 4T1 Tumor Bearing Mice
Figure 6
TET inhibits in vivo blood perfusion in 4T1 tumor bearing mice. (a) In vivo LDPI imaging of mice. TET was orally administered (10 mg/kg, once/2 days). With a distance of 10 cm between the scanner and the skin surface, three examined areas (1.4 1.4 cm) covered the tumor (Flux 1), adjacent healthy skin around tumor (Flux 2), and the heart of mice (Flux 3). (b and c) Quantitative analysis of microvascular blood perfusion in mice. Related perfusion (Flux 1) = ; related perfusion (Flux 2) = . *, ** versus vehicle control.
