Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 10

Research Article

Vitamin K2, a Naturally Occurring Menaquinone, Exerts Therapeutic Effects on Both Hormone-Dependent and Hormone-Independent Prostate Cancer Cells

Figure 10

Effects of VK2 on the growth of LNCaP, 22 RV1, and DU145 xenografts in nude mice: VK2 inhibits the growth of LNCaP, 22RV1 and DU145 derived tumor xenografts in nude mice model. Tumor volume (mm3) and weights (gms) of the VK2 treated and control untreated tumors of the nude mice were measured at the end of the study. Six independent tumors were collected from the VK2 treated LNCaP, 22RV1, and DU-145 and untreated control nude mice, respectively. Results (a–f) showed that VK2 significantly (* ) reduced the tumor weight and tumor volumes of both androgen-dependent and androgen-independent derived prostate cancer cells implanted in nude mice compared to control groups.
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