Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 4

Research Article

Efficacy of Plectranthus amboinicus (Lour.) Spreng in a Murine Model of Methicillin-Resistant Staphylococcus aureus Skin Abscesses

Table 4

Minimal inhibitory concentration of extracts, fractions, and subfractions of P. amboinicus against MRSA clinical isolates and ATCC.

StrainControlsExtracts
FractionsSubfractions
Van
   (mg/mL)
DMSO
(μg/mL)
Bact
(% v/v)
EH
(mg/mL)
ET
(mg/mL)
F1F2F3F4F5F4aF4bF4cF4dF4eF4fF4g

ATCC 259231no+48nonono0.5no20.50.50.5nonono
ATCC 653981no+44nonono0.5no10.50.50.5nonono
MRSA 012no+48nonono0.5no10.50.50.5nonono
MRSA 022no+24nonono0.5no20.50.50.5nonono
MRSA 031no+28nonono0.25no10.50.50.5nonono
MRSA 041no+28nonono0.5no
MRSA 051no+44nonono0.5no
MRSA 062no+48nonono0.25no
MRSA 072no+28nonono0.5no
MRSA 081no+24nonono0.5no
MRSA 092no+28nonono0.5no
MRSA 101no+24nonono0.5no
MRSA 112no+28nonono0.5no
MRSA 122no+28nonono0.5no
MRSA 132no+28nonono0.25no
MRSA 142no+28nonono0.5no

Bact: bacteria; CT: growth control; EH: hydroalcoholic extract; ET: ethanolic extract; F1: hexane fraction; F2: petroleum ether fraction; F3: dichloromethane fraction; F4: ethyl acetate fraction; F5: methanol fraction; F4a–g: subfractions of fraction F4; Van: vancomycin; DMSO: dimethyl sulfoxide; no: no activity.