Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF-κB-Associated Nitric Oxide and Prostaglandin E₂ production

Figure 2

Inhibition of carrageenan-induced paw swelling and infiltration of inflammatory cells by EER. (a) Histomorphometry of the ventrum pedis skin. In each rats, cutaneous regions of ventrum pedis were stained with H and E and used for histological sample preparation in this study. Arrow indicated total thicknesses measured. Scale bars = 160 μm. (b) Thickness of epidermis to dermis. Data represents the mean ± S.E.M. of five animals (significant as compared with carrageenan alone,  ^∗∗𝑃<0.01). (c) Histopathology of the ventrum pedis stained with H and E. Scale bars = 160 μm. (d) Infiltration of inflammatory cells. Data represents the mean ± S.E.M. of five animals (significant as compared with carrageenan alone, ^∗∗𝑃<0.01). EERs: extract of Erigeron annuus roots.