Research Article
Curative Effects of ZHENG-Based Fuzheng-Huayu Tablet on Hepatitis B Caused Cirrhosis Related to CYP1A2 Genetic Polymorphism
Table 6
Correlation between CYP1A2 Genotypes and FZHY efficacy on ZHENG score in HBC.
| | Genotypes | Effective (%) | Invalid (%) | | OR | 95% CI |
| | CYP1A2-5347 | | | | | | | CC | 48 (71.60) | 32 (72.70) | | | | | CT | 17 (25.40) | 9 (20.50) | 0.624 | 0.794 | 0.315, 2.000 | | TT | 0 (0) | 2 (4.50) | | | | | CT + TT | 17 (25.40) | 11 (25.00) | 0.947 | 0.971 | 0.402, 2.341 | | CYP1A2-2964 | | | | | | | GG | 33 (49.30) | 23 (52.30) | | | | | GA | 30 (44.80) | 11 (25.00) | 0.146 | 0.526 | 0.220, 1.258 | | AA | 3 (4.50) | 10 (22.70) | 0.030 | 4.783 | 1.184, 19.321 | | GA + AA | 33 (49.30) | 21 (47.70) | 0.815 | 0.913 | 0.426, 1.959 | | CYP1A2-733 | | | 0.527 | | | | CC | 9 (13.40) | 3 (6.80) | | | | | CA | 27 (40.30) | 20 (45.50) | 0.266 | 2.222 | 0.532, 9.275 | | AA | 30 (44.80) | 21 (47.70) | 0.299 | 2.100 | 0.507, 8.694 | | CA + AA | 57 (85.10) | 41 (93.20) | 0.261 | 2.158 | 0.550, 8.466 |
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The bold font emphasizes the result was statistically significant ()
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