Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 7

Research Article

Curative Effects of ZHENG-Based Fuzheng-Huayu Tablet on Hepatitis B Caused Cirrhosis Related to CYP1A2 Genetic Polymorphism

Table 7

Correlation between CYP1A2 genotype and ZHENG types in FZHY efficacy.

GenotypesExcess ZHENG Deficiency-Excess ZHENG Deficiency ZHENG
Effective (%) 
Invalid (%) 
Effective (%) 
Invalid (%) 
Effective (%) 
Invalid (%) 

CYP1A2-5347
 CC27 (69.23)20 (66.67)8 (80.00)8 (72.73)14 (77.78)2 (66.67)
 CT11 (28.21)5 (16.67)0.4252 (20.00)3 (27.27)1.0004 (22.22)1 (33.33)1.000
 TT0 (0)2 (6.67)0 (0)0 (0)0 (0)0 (0)
 CT + TT11 (28.21)7 (23.33)0.7882 (20.00)3 (27.27)1.0004 (22.22)1 (33.33)1.000
CYP1A2-2964
 GG17 (43.59)15 (50.00)7 (70.00)5 (45.45)1 (5.56)2 (66.67)
 GA19 (48.72)7 (23.33)0.1193 (30.00)3 (27.27)1.00012 (66.67)1 (33.33)0.071
 AA3 (7.69)6 (20.00)0.4540 (0)3 (27.27)5 (27.78)0 (0)
 GA + AA22 (56.41)13 (43.33)0.4203 (30.00)6 (54.55)0.38717 (94.44)1 (33.33)0.041
CYP1A2-733
 CC5 (12.82)2 (6.67)2 (20.00)1 (9.09)2 (11.11)0 (0)
 CA14 (35.89)13 (43.33)0.4266 (60.00)4 (36.36)1.0008 (44.44)2 (66.67)
 AA20 (51.28)13 (43.33)0.6912 (20.00)6 (54.55)0.4918 (44.44)1 (33.33)
 CA + AA34 (87.18)26 (86.67)0.4548 (80.00)10 (90.91)0.58616 (88.88)3 (100.00)

The bold font emphasizes the result was statistically significant ( )

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