Research Article

High-Frequency Ultrasound Imaging to Evaluate Liver Fibrosis Progression in Rats and Yi Guan Jian Herbal Therapeutic Effects

Figure 5

Fibrotic gene expression levels of α-SMA and Col α-1.I in normal control rats, DMN-induced fibrosis rats, and YGJ herb-treated rats. (a) Gene expression patterns were amplified by semiquantitative RT-PCR in four different groups including the normal control rats, 2-week DMN-treated rats, 4-week DMN-treated with 2-week PBS rats, and 4-week DMN-treated with 2-week YGJ rats . (b) The expression levels of α -SMA and Col α -1.I were quantified using densitometry. Values were normalized against those for GAPDH mRNA expression as an internal calculation control. ; compared with the normal control group. ; compared with 4-week DMN-treated group.
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