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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 302325, 11 pages
http://dx.doi.org/10.1155/2013/302325
Research Article

High-Frequency Ultrasound Imaging to Evaluate Liver Fibrosis Progression in Rats and Yi Guan Jian Herbal Therapeutic Effects

1Department of Life Sciences, Agricultural Biotechnology Center, iEGG Center, National Chung Hsing University, Kuo Kuang Road, Taichung 402, Taiwan
2Division of Pulmonary and Critical Care Medicine, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan
3Center for Nanomedicine Research, National Health Research Institutes, Miaoli 350, China
4Department of Bioresources, Da-Yeh University, Changhwa 515, Taiwan
5Taichung Armed Forces General Hospital, Taichung 411, Taiwan
6Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan 333, Taiwan
7Department of Veterinary Medicine, National Chung Hsing University, Taichung 402, Taiwan

Received 1 June 2013; Revised 4 September 2013; Accepted 4 September 2013

Academic Editor: Qing He

Copyright © 2013 Wei Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. P. Anthony, K. G. Ishak, N. C. Nayak, H. E. Poulsen, P. J. Scheuer, and L. H. Sobin, “The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization,” Journal of Clinical Pathology, vol. 31, no. 5, pp. 395–414, 1978. View at Google Scholar
  2. R. Bataller and D. A. Brenner, “Liver fibrosis,” Journal of Clinical Investigation, vol. 115, no. 2, pp. 209–218, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Guimond, M. Teletin, E. Garo et al., “Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice,” Liver International, vol. 27, no. 6, pp. 854–864, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. V. M. R. de Lima, C. P. M. S. Oliveira, V. A. F. Alves et al., “A rodent model of NASH with cirrhosis, oval cell proliferation and hepatocellular carcinoma,” Journal of Hepatology, vol. 49, no. 6, pp. 1055–1061, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. G. Yan, Y. Duan, L. Ruan, Y. Yang, and T. Cao, “Experimental study on the relation between the noninvasive ultrasonography quantitative scoring system and the degree of the hepatic fibrosis,” Hepato-Gastroenterology, vol. 54, no. 79, pp. 1908–1914, 2007. View at Google Scholar · View at Scopus
  6. T. Matsuhashi, N. Yamada, H. Shinzawa, and T. Takahashi, “An evaluation of hepatic ultrasound speed in injury models in rats: correlation with tissue constituents,” Journal of Ultrasound in Medicine, vol. 15, no. 8, pp. 563–570, 1996. View at Google Scholar · View at Scopus
  7. F. S. Foster, M. Y. Zhang, Y. Q. Zhou et al., “A new ultrasound instrument for in vivo microimaging of mice,” Ultrasound in Medicine and Biology, vol. 28, no. 9, pp. 1165–1172, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. F. S. Foster, C. J. Pavlin, K. A. Harasiewicz, D. A. Christopher, and D. H. Turnbull, “Advances in ultrasound biomicroscopy,” Ultrasound in Medicine and Biology, vol. 26, no. 1, pp. 1–27, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. D. A. Knapik, “A 100-200 MHz ultrasound biomicroscope,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 47, no. 6, pp. 1540–1549, 2000. View at Publisher · View at Google Scholar · View at Scopus
  10. D. E. Goertz, J. L. Yu, R. S. Kerbel, P. N. Burns, and F. S. Foster, “High-frequency 3-D color-flow imaging of the microcirculation,” Ultrasound in Medicine and Biology, vol. 29, no. 1, pp. 39–51, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Grassi, C. Cavaliere, S. Cozzolino et al., “Small animal imaging facility: new perspectives for the radiologist,” Radiologia Medica, vol. 114, no. 1, pp. 152–167, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Y. Chen, H. L. Chen, S. H. Wu et al., “Application of high-frequency ultrasound for the detection of surgical anatomy in the rodent abdomen,” Veterinary Journal, vol. 191, no. 2, pp. 246–252, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. Y. Yang, S. Yang, M. Chen, X. Zhang, Y. Zou, and X. Zhang, “Compound Astragalus and Salvia miltiorrhiza Extract exerts anti-fibrosis by mediating TGF-β/Smad signaling in myofibroblasts,” Journal of Ethnopharmacology, vol. 118, no. 2, pp. 264–270, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. J.-L. Lou, M.-N. Jiang, C. Li et al., “Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model,” Journal of Ethnopharmacology, vol. 128, no. 1, pp. 131–138, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. H.-J. Lin, J.-Y. Chen, C.-F. Lin et al., “Hepatoprotective effects of Yi Guan Jian, an herbal medicine, in rats with dimethylnitrosamine-induced liver fibrosis,” Journal of Ethnopharmacology, vol. 134, no. 3, pp. 953–960, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. S.-T. Kao, H.-J. Lin, C.-P. Tseng et al., “A Chinese herbal decoction, modified Yi Guan Jian, induces apoptosis in hepatic stellate cells through an ROS-mediated mitochondrial/caspase pathway,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 459531, 8 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. Mu, P. Liu, G. Du et al., “Action mechanism of Yi Guan Jian decoction on CCl4 induced cirrhosis in rats,” Journal of Ethnopharmacology, vol. 121, no. 1, pp. 35–42, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Nishikawa, N. Ohi, A. Yagisawa et al., “Suppressive effect of orthovanadate on hepatic stellate cell activation and liver fibrosis in rats,” American Journal of Pathology, vol. 174, no. 3, pp. 881–890, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Y. Chen, H. L. Chen, J. C. Cheng et al., “A Chinese herbal medicine, Gexia-Zhuyu Tang (GZT), prevents dimethyl nitrosamine-induced liver fibrosis through inhibition of hepatic stellate cells proliferation,” Journal of Ethnopharmacology, vol. 142, no. 3, pp. 811–818, 2012. View at Publisher · View at Google Scholar
  20. C.-H. Hung, S.-N. Lu, J.-H. Wang et al., “Correlation between ultrasonographic and pathologic diagnoses of hepatitis B and C virus-related cirrhosis,” Journal of Gastroenterology, vol. 38, no. 2, pp. 153–157, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. C.-C. Yen, C.-Y. Lin, K.-Y. Chong et al., “Lactoferrin as a natural regimen for selective decontamination of the digestive tract: recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonates from pathogenic challenge in the gastrointestinal tract,” Journal of Infectious Diseases, vol. 199, no. 4, pp. 590–598, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. C.-C. Yen, Y.-W. Lai, H.-L. Chen et al., “Aerosolized human extracellular superoxide dismutase prevents hyperoxia-induced lung injury,” PLoS ONE, vol. 6, no. 10, Article ID e26870, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. C.-M. Hung, C.-C. Yeh, H.-L. Chen et al., “Porcine lactoferrin administration enhances peripheral lymphocyte proliferation and assists infectious bursal disease vaccination in native chickens,” Vaccine, vol. 28, no. 16, pp. 2895–2902, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. F.-C. Liu, H.-L. Chen, W. Lin et al., “Application of porcine lipase secreted by pichia pastoris to improve fat digestion and growth performance of postweaning piglets,” Journal of Agricultural and Food Chemistry, vol. 58, no. 6, pp. 3322–3329, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. P. Starkel and I. A. Leclercq, “Animal models for the study of hepatic fibrosis,” Best Practice and Research Clinical Gastroenterology, vol. 25, no. 2, pp. 319–333, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Hayashi and T. Sakai, “Animal models for the study of liver fibrosis: new insights from knockout mouse models,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 300, no. 5, pp. G729–G738, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Constandinou, N. Henderson, and J. P. Iredale, “Modeling liver fibrosis in rodents,” Methods in Molecular Medicine, vol. 117, pp. 237–250, 2005. View at Google Scholar · View at Scopus
  28. J. P. Iredale, “Hepatic stellate cell behavior during resolution of liver injury,” Seminars in Liver Disease, vol. 21, no. 3, pp. 427–436, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. G. Layer, I. Zuna, A. Lorenz et al., “Computerized ultrasound B-scan texture analysis of experimental diffuse parenchymal liver disease: correlation with histopathology and tissue composition,” Journal of Clinical Ultrasound, vol. 19, no. 4, pp. 193–201, 1991. View at Google Scholar · View at Scopus
  30. D. S. Biller, B. Kantrowitz, and T. Miyabayashi, “Ultrasonography of diffuse liver disease. A review,” Journal of Veterinary Internal Medicine, vol. 6, no. 2, pp. 71–76, 1992. View at Google Scholar · View at Scopus
  31. M. H. Wang, M. L. Palmeri, C. D. Guy et al., “In vivo quantification of liver stiffness in a rat model of hepatic fibrosis with acoustic radiation force,” Ultrasound in Medicine and Biology, vol. 35, no. 10, pp. 1709–1721, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. M.-C. Ho, J.-J. Lin, Y.-C. Shu et al., “Using ultrasound Nakagami imaging to assess liver fibrosis in rats,” Ultrasonics, vol. 52, no. 2, pp. 215–222, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. I. Fernández-Domínguez, J. J. Echevarria-Uraga, N. Gómez et al., “High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice,” Ultrasound in Medicine and Biology, vol. 37, no. 7, pp. 1161–1169, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. T. Nishiura, H. Watanabe, M. Ito et al., “Ultrasound evaluation of the fibrosis stage in chronic liver disease by the simultaneous use of low and high frequency probes,” British Journal of Radiology, vol. 78, no. 927, pp. 189–197, 2005. View at Publisher · View at Google Scholar · View at Scopus
  35. S. G. J. Williams, J. E. Evanson, N. Barrett, M. E. Hodson, J. E. Boultbee, and D. Westaby, “An ultrasound scoring system for the diagnosis of liver disease in cystic fibrosis,” Journal of Hepatology, vol. 22, no. 5, pp. 513–521, 1995. View at Publisher · View at Google Scholar · View at Scopus
  36. Y. Xu, B. Wang, and H. Cao, “An ultrasound scoring system for the diagnosis of liver fibrosis and cirrhosis,” Chinese Medical Journal, vol. 112, no. 12, pp. 1125–1128, 1999. View at Google Scholar · View at Scopus
  37. B. Ou, D. Huang, M. Hampsch-Woodill, and J. A. Flanagan, “When east meets west: the relationship between yin-yang and antioxidation-oxidation,” The FASEB Journal, vol. 17, no. 2, pp. 127–129, 2003. View at Publisher · View at Google Scholar · View at Scopus
  38. M. G. Sturgill and G. H. Lambert, “Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and methods of monitoring hepatic function,” Clinical Chemistry, vol. 43, no. 8, pp. 1512–1526, 1997. View at Google Scholar · View at Scopus