Evidence-Based Complementary and Alternative Medicine

Research Article

Strychnos pseudoquina and Its Purified Compounds Present an Effective In Vitro Antileishmanial Activity

Table 4

Treatment of infected macrophages.
ProductsConcentrationPercentage of infected macrophages after
treatment/number of amastigotes per cella
Ethyl acetate extract
(μg/mL)		100 48.9/1.7
50 50.0/1.8
25 70.3/4.4
087.0/8.4
Quercetin 3-O-methyl ether (μM)280 46.3/1.7
140 68.0/ 4.4
70 72.4/5.6
087.0/8.4
Strychnobiflavone
(μM)		1609.6/0.4
80 26.3/1.3
40 37.9/1.5
087.0/8.4
The percentage of infected macrophages and the number of amastigotes per cell were determined by counting 200 cell coverslips, performed in triplicate. Values are representative from four independent experiments, which presented similar results.