Electroacupuncture Attenuates 5′-Guanidinonaltrindole-Evoked Scratching and Spinal c-Fos Expression in the Mouse

<table>Effects of EA at 2 Hz on GNTI- (0.3 mg/kg) induced scratching in naloxone-pretreated mice. Naloxone (s.c.; 1 mg/kg) was administered 70 min before GNTI injection, that is, 5 min before isoflurane anesthesia for EA. EA was applied to the LI4 and LI11 acupoints before GNTI administration. The number of scratches was counted for a period of 40 min after pruritogen injection. EA failed to attenuate GNTI-induced scratching behavior in naloxone-pretreated mice. Between-group comparisons for each group were performed by Student’s <svg height="10.3875" id="M20" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 5.9250002 10.3875" width="5.9250002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>-test.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Electroacupuncture Attenuates 5′-Guanidinonaltrindole-Evoked Scratching and Spinal c-Fos Expression in the Mouse 