Research Article

Electroacupuncture Attenuates 5′-Guanidinonaltrindole-Evoked Scratching and Spinal c-Fos Expression in the Mouse

Figure 6

Effects of EA at 2 Hz on GNTI- (0.3 mg/kg) induced scratching in nor-binaltorphimine-pretreated mice. Nor-binaltorphimine (10 mg/kg) was subcutaneously administered 24 hr before GNTI injection [25]. EA was applied to the LI4 and LI11 acupoints before GNTI administration. The number of scratches was counted for 40 min after pruritogen injection. EA attenuated GNTI-induced scratching behavior in nor-binaltorphimine-pretreated mice (* ). Between-group comparisons for each group were performed by Student’s -test.
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