Research Article
The rs1142345 in TPMT Affects the Therapeutic Effect of Traditional Hypoglycemic Herbs in Prediabetes
Table 4
Significant SNPs for multinomial logistic regression.
| SNP | Gene | Allele | Chr | Position | MAF* | P | FDR p |
| rs1142345 | TPMT | A/G | 6 | 18130918 | 0.229 | 0.001 | 0.043 | rs2306168 | SLCO2B1 | T/C | 11 | 74907582 | 0.305 | 0.003 | 0.129 | rs2231142 | ABCG2 | A/C | 4 | 89052323 | 0.260 | 0.021 | 0.903 | rs717620 | ABCC2 | C/T | 10 | 101542578 | 0.230 | 0.023 | 0.989 | rs1799931 | NAT2 | A/G | 8 | 18258370 | 0.153 | 0.024 | 1 | rs4244285 | CYP2C19 | A/G | 10 | 96541616 | 0.344 | 0.027 | 1 | rs4124874 | UGT1A1 | G/T | 2 | 234665659 | 0.337 | 0.044 | 1 |
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Minor allele frequency calculated from the subjects.
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