Activation of MITF by Argan Oil Leads to the Inhibition of the Tyrosinase and Dopachrome Tautomerase Expressions in B16 Murine Melanoma Cells
Figure 3
Effect of argan oil on the expressions of the phosphorylated extracellular signal-regulated kinases 1/2 (pERK1/2), ERK1, ERK2, phosphorylated microphthalmia-associated transcription factor (pMITF), and total MITF proteins (a) and their densitometric values (b). B16 melanoma cells were cultured in 100 mm dish at a density of cells/dish and treated without (CT) or with 1 µM hirsein A (HA) or 1/1000 v/v argan oil (AO).
