Review Article

Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Table 13

Apoptosis in cocultures of T cells and pancreatic β cells [46].

Cell/Medium% Apoptosis and
necrosis

CD4+ T cells/control medium<4
CD4+ T cells/with PBS-treated β cells
of NOD-SCID mice
2
CD4+ T cells/with cytopiloyne-treated β cells 18
CD4+ T cells/with cytopiloyne-treated β cells in
the presence of α-FasL antibody
7
CD8+ T cells/control medium4
CD4+ T cells/with PBS-treated β cells
of NOD-SCID mice
4
CD8+ T cells/with cytopiloyne-treated β cells4
CD8+ T cells/with cytopiloyne-treated β cells in
the presence of α-FasL antibody
4