Antidiabetic Activity of Polysaccharides from Tuberous Root of Liriope spicata var. prolifera in KKAy Mice
Figure 5
Immunoperoxidase stainings analysis of InsR-α (a), IRS-1 (b), PI3K (c), and PPARγ (d) in liver tissues of KKAy mice. Protein expression was mainly expressed in the hepatic cells of the normal control group, which was suppressed in the diabetic control obese KKAy mice. Compared with the diabetic mice, protein levels of polysaccharide treated obese KKAy mice were significantly increased. (A) Diabetic control obese KKAy mice; (B) obese KKAy mice treated with rosiglitazone; (C) normal control C57BL/6J mice; (D)-(E) obese KKAy mice treated with TLSP (200; 100 mg·kg−1·day−1); (F)-(G) obese KKAy mice treated with LSP1 (200; 100 mg·kg−1·day−1); (H)-(I) obese KKAy mice treated with LSP2 (200; 100 mg·kg−1·day−1).
