A Valid Approach in Refractory Glossodynia: A Single-Institution 5-Year Experience Treating with Japanese Traditional Herbal (Kampo) Medicine

Table 1

Composition and herb doses of the 6 most effective Kampo prescriptions for glossodynia.

Seinetsuhokito
Ginseng Root (3), Angelica Root (3), Peony Root (3), Ophiopogon Tuber (3),
Atractylodes Rhizome (3.5), Hoelen (3.5), Cimicifuga Rhizome (1),
Schisandra Fruit (1), Scrophularia Buergeriana Root (1), and Glycyrrhiza Root (1)
Mibakuekkito
Astragalus Root (4), Glycyrrhiza Root (1.5), Jujube Fruit (2), Ginseng Root (4),
Atractylodes Rhizome (4), Ginger Rhizome (1), Angelica Root (3),
Citrus Unshiu Peel (2), Cimicifuga Rhizome (0.5), Bupleurum Root (2),
Schisandra Fruit (2), and Ophiopogon Tuber (5)
Kamishoyosan
Bupleurum Root (3), Peony Root (3), Atractylodes Lancea Rhizome (3),
Angelica Root (3), Hoelen (3), Gardenia Fruit (2), Moutan Bark (2),
Glycyrrhiza Root (1.5), Ginger Rhizome (1), and Mentha Herb (1)
Orento
Pinellia Tuber (6), Coptis Rhizome (3), Glycyrrhiza Root (3), Cinnamon Bark (3),
Jujube Fruit (3), Ginseng Root (3), and Ginger Rhizome (3)
Bukuryoingohangekobokuto
Pinellia Tuber (6), Hoelen (5), Atractylodes Lancea Rhizome (4), Magnolia Bark (3),
Citrus Unshiu Peel (3), Ginseng Root (3), Perilla Herb (2), Immature Orange (1.5),
and Ginger Rhizome (1)
Ji’inshihoto
Cyprus Rhizome (3), Bupleurum Root (3), Peony Root (3), Anemarrhena Rhizome (3),
Citrus Unshiu Peel (3), Angelica Root (3), Ophiopogon Tuber (3),
Atractylodes Rhizome (3), Hoelen (3), Glycyrrhiza Root (1), Mentha Herb (1),
Lycium Bark (3), and Fritillary Bulb (2)

Seinetsuhokito and mibakuekkito are decoction medicines, and kamishoyosan, orento, bukuryoingohangekobokuto, and ji’inshihoto are extract-granule medicines. The numbers in the round brackets show the one-day dose of each herb (grams).