Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice

Figure 1

Evaluations of stereotypy of TS mice model in different groups during an 8-week period. The scores were recorded every 7 d. The initial scores before treatments showed no differences among groups (𝑃>0.05). However, there was a gradual increase in the scores in IDPN mice. Treatments of either Tia or JPZDD gradually decreased the stereotypy scores staring from 3 w of treatment. In addition, more significant reduction of stereotypy scores were observed in JPZDD treated mice. Data were indicated as the mean ± SEM (𝑛=20 mice/group); ∗ indicates the 𝑃<0.05 compared with IDPN group; # indicates the 𝑃<0.05 compared with Tia group.