The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors

Table 1

The IC50 of AS-M in brain tumors and normal cells.

Cell line	Tumor type	IC50 of AS-M (𝜇g/mL)
Brain tumors
DBTRG-05MG	Human GBM cell	25.5 ± 11.0*
G5T/VGH	Human GBM cell	21.1 ± 6.8*
N18	Mouse neuroblastoma	40.3 ± 1.3*
Normal cells
Balb/3T3	Mouse fibroblast cell	>400

Note: values are mean ± SD IC₅₀ (𝜇g/mL) after treatment for 48 h.
*Significant difference from the brain tumors versus normal cells of AS-M treatment (𝑃<0.001).