The Protective Role of Resveratrol against Arsenic Trioxide-Induced Cardiotoxicity

Figure 5

The effect of resveratrol on As₂O₃-inducedHO-1 and Nrf2 on the mRNA level in the heart from the control, As₂O₃-treated, resveratrol + As₂O₃, and resveratrol-treated groups. (a) Real-time quantitative PCR analyses of gene expression levels of HO-1 in cardiac myocytes. (b) Real-time quantitative PCR analyses of gene expression levels of Nrf2 in cardiac myocytes. Values are mean ± S.E. mean; 𝑛=8. *𝑃<0.05 or **𝑃<0.01 versus control group, ^#𝑃<0.05 or ^##𝑃<0.01 versus As₂O₃-treated group.

(a)

(b)