Review Article
Amyloidosis in Alzheimer’s Disease: The Toxicity of Amyloid Beta (Aβ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy
Table 1
Some examples of amyloid proteins, their functional precursors, and related diseases.
| Amyloid protein (abbreviation) | Precursor protein | Disease | Distribution/type | Reference |
| Aβ | Aβ precursor protein | Alzheimer’s disease | Localized/hereditary or Acquired | [57] | Aβ | Aβ precursor protein | Cerebral amyloid angiopathy | Localized/hereditary | [58] | AIAPP | Pro-IAPP | Diabetes mellitus type II | Localized/??? | [59] | AL | Immunoglobulin light chain | Primary systemic amyloidosis | Systemic/acquired | [60] | AA | Serum amyloid A | Rheumatoid arthritis | Systemic/acquired | [61] | ATTR | Wild-type transthyretin | Senile systemic amyloidosis | Systemic/acquired | [62] | ATTR | Transthyretin variant | Familial amyloid polyneuropathy | Systemic/hereditary | [63] | AFib | Fibrinogen α-chain variant | Familial amyloidosis | Systemic/hereditary | [64] | Aβ2M | Beta 2 microglobulin | Hemodialysis-associated amyloidosis | Systemic/acquired | [65] | APrPSC | Prion protein | Creutzfeldt-Jakob disease | Localized/hereditary | [66] | AANF | Atrial natriuretic factor | Isolated atrial amyloidosis | Localized/acquired | [67] |
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