Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats

Table 2

Biochemical and hematological parameters of animals exposed to Jacaranda decurrens in the subacute toxicity study.

Parameter	Control (vehicle)	250 mg/kg	500 mg/kg	1000 mg/kg
Creatinine (mg/dL)	1.20±0.15	1.50±0.10	1.20±0.10	1.50±0.10
Urea ( mg/dL)	49.50±3.80	54.60±3.60	53.00±4.50	47.90±3.50
AST (U/L)	114.40±19.40	98.40±13.20	100.20±17.40	104.60±24.40
ALT (U/L)	20.80±2.60	25.20±4.00	22.80±1.70	23.60±3.50
δ-GT (U/L)	11.78±0.70	13.30±2.10	12.60±0.80	13.30±2.10
Erythrocyte count (×10^6) mm^3	7.50±0.45	6.70±0.50	6.70±2.00	7.30±1.70
Hematocrit (%)	39.50±1.90	42.60±0.60	44.10±1.10	42.50±2.00
Platelet count (×10^3/µL)	1064.00±48.00	1051.00±20.00	1070.00±27.00	1069.00±32.00
Lymphocytes (%)	69.80±4.30	78.00±1.10	76.30±2.20	80.00±1.64
Eosinophils (%)	1.10±0.10	1.10±0.10	1.10±0.10	1.10±0.10
Monocyte (%)	2.90±0.40	3.20±0.20	2.80±0.40	3.30±0.20
Neutrophils (%)	25.30±4.60	23.80±2.10	22.00±1.00	21.20±0.70

Values expressed as mean ± SEM, 𝑛=8 animals/group. 𝑃>0.05 by ANOVA.