Research Article

Antiproliferative Action of Conjugated Linoleic Acid on Human MCF-7 Breast Cancer Cells Mediated by Enhancement of Gap Junctional Intercellular Communication through Inactivation of NF-κB

Figure 1

Viability of MCF-7 cells treated with CLA isomers. (a) Cells treated with 5 μM (■), 10 μM (▲), 20 μM (∆), and 40 μM (●) concentrations of c9,t11-CLA and control (♦) for 72 h. (b) Cells treated with 40 μM c9,t11-CLA (▲), t10,c12 -CLA (∆), and LA (■) and control cells (♦) for 48 h. Values are expressed as means ± standard deviations ( ). Means with different lower case letters or with different upper case letters on different concentration lines at the same incubation time are significantly different at by Duncan’s multiple-range test.