Research Article

Emu Oil Reduces Small Intestinal Inflammation in the Absence of Clinical Improvement in a Rat Model of Indomethacin-Induced Enteropathy

Table 3

Body weight (% change from starting body weight), total food (g) and water (mL) intake and total fecal (g) and urine (mL) output in rats during Indomethacin administration (days 5–12). Rats were gavaged daily with Water, Olive Oil, or Emu Oil (0.5 mL) throughout the experimental period and commenced daily gavage with water or Indomethacin (Indo; 8 mg/kg) on day 5. Rats were fasted overnight on day 11 and therefore day 12 body weight data was not included.

Water + WaterIndo + WaterIndo + Olive OilIndo + Emu Oil

Body weight (%)23.1 ± 0.81.6 ± 3.3***6.0 ± 2.44.6 ± 2.0
Food intake (g)132.8 ± 1.678.2 ± 4.9***83.9 ± 4.377.9 ± 4.4
Water intake (mL)416 ± 51.3715.1 ± 72.1**651.7 ± 53.1655.9 ± 66.1
Fecal ouput (g)12.8 ± 0.410.1 ± 0.6**12.4 ± 12.4 ±
Urine ouput (mL)104.2 ± 8.587.8 ± 3.185.4 ± 6.298.8 ± 7.3

Data are expressed as mean (%, g or mL) ± standard error of the mean. *** , ** compared to Water + Water; compared to Indomethacin + Water.