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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 429738, 9 pages
Research Article

Chinese Medicine Formula Lingguizhugan Decoction Improves Beta-Oxidation and Metabolism of Fatty Acid in High-Fat-Diet-Induced Rat Model of Fatty Liver Disease

1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
2Shanghai East Hospital, Tongji University, Shanghai 200120, China
3Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China
4E-Institute of Shanghai Municipal Education Commission, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Received 21 March 2013; Accepted 11 April 2013

Academic Editor: Yong Qing Yang

Copyright © 2013 Tao Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

An Agilent 1100 HPLC system consisting of a G1354A pump, a G1313A auto-sampler, and a UV Detector was used for all analyses. Chromatographic separations were carried out on an Merck C18 hibar column (4.6 mm×250 mm,5 µm) with methanol:acetonitrile:water:acetid acid (15:35:45:0.9,v/v) in the mobile phase at a flow rate of 0.8 mL/min at 25°C for 40 min. The HPLC fingerprint of lingguizhugan decoction revealed the major peaks (glycyrrhizic acid) at 254 nm. The content of glycyrrhizic acid were 0.9548%.

  1. Supplementary Material