Proteomic Analysis of the Effect of Acupuncture on the Suppression of Kainic Acid-Induced Neuronal Destruction in Mouse Hippocampus

Table 1

Differentially expressed protein profiles of the protein spots after acupuncture stimulation at HT8.

Name	Theoretical		Gel		MASCOT score	Peptides matched	Sequence coverage (%)	Average ratio^a
	Mr (kD)	pI	Mr (kD)	pI				KA/Saline	KA + HT8/; KA	KA + HT8/; Saline
Valosin containing protein, isoform CRA_a	90.868	5.14	89.7	5.13	276	34	47	2.103*	−1.324	1.588
Ubiquitin-like modifier-activating enzyme 1 isoform 1	118.931	5.43	103.11	5.24	160	24	30	−3.576*	1.259	−2.841*
ATP synthase subunit d, mitochondrial	18.795	5.52	28.02	5.50	133	15	67	−1.631*	−1.471	−2.400*
Heat shock 70 kDa protein 4L	95.178	5.54	101.62	5.69	257	29	39	−1.321**	−1.245	−1.645**
Heat shock protein 4 like, isoform CRA_c	101.159	5.73	101.34	5.84	280	30	35	−1.718*	−1.480	−2.543**
Dihydropyrimidinase-related protein 2	62.638	5.95	56.96	5.87	210	26	53	−1.897**	1.417*	−1.339
Transcriptional activator protein Pur-alpha	34.976	6.07	46.54	6.20	110	11	38	−1.329	2.949*	2.220*
Pyruvate dehydrogenase protein X component, mitochondria	54.250	7.63	53.67	6.29	86	12	23	−1.189	1.523*	1.281
Serine/threonine-protein phosphatase 5	57.437	5.83	60.31	6.50	79	14	27	−1.293	1.688*	2.182*
T-complex protein 1 subunit alpha	60.867	5.82	64.14	6.53	177	21	44	−1.232	1.683*	1.366*
Uncharacterized protein LOC433182	47.453	6.37	50.76	7.20	221	24	55	−1.120	1.458*	1.302*

Saline: saline-injected group; KA: KA-injected group; KA + HT8: KA-injected group with acupuncture stimulation at HT8 acupoint. ^aAverage ratio calculated considering 3 replicate gels. A minus means that the protein expression was decreased. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 between the groups.