Inhibition of Acute Phase Inflammation by Laminaria japonica through Regulation of iNOS-NF-κB Pathway

Table 1

Changes on the histomorphometrical analysis of hind paw skins in the present study (group summary).

Groups	Dorsum pedis skin		Ventrum pedis skin
	Thickness; (epidermis to dermis; mm)	Infiltrated inflammatory cells (cells/mm^2 of cutaneous regions)	Thickness (mm)	Infiltrated inflammatory cells (cells/mm^2 of cutaneous regions)
Controls
Carrageenan	2.424±0.471	118.40±55.25	1.133±0.078	1358.80±332.34
Reference
Dexamethasone	1.073±0.144^a	24.00±6.96^c	0.790±0.136^a	102.60±38.33^c
LJE treated as
0.1	1.792±0.239^a	62.40±11.15^d	1.006±0.048^b	433.60±355.78^d
0.3	1.594±0.254^a	54.40±3.98^c	0.880±0.064^a	152.00±67.31^c

Values are expressed as mean ± SD of 5 rat’s hind paws.
^a𝑃<0.01 and ^b𝑃<0.05 compared to carrageenan control by LSD test.
^c𝑃<0.01 and ^d𝑃<0.05 compared to carrageenan control by MW test.