Research Article

α-Mangostin from Cratoxylum arborescens (Vahl) Blume Demonstrates Anti-Ulcerogenic Property: A Mechanistic Study

Table 1

Observed ulcer area, inhibition percentage pH and mucus content stomach.

Animal groupPre-treatment (5 mL/kg dose)pH of gastric contentMucus contentUlcer index (mm)2
(Mean ± S.E.M)
Inhibition (%)

1Tween80 (normal control)
2Ethanol 95% (ulcer control)
3Omeprazole (20 mg/kg) 78.42
4α-mangostin (10 g/kg) 66.04
5α-mangostin (30 mg/kg) 74.39

All values are expressed as mean ± standard error of the mean. Means with different superscripts are significantly different. The mean difference is significant at the 0.05 level. Groups with different superscript alphabets are statistically significant.