Ginsenoside Rb1 Reduces Isoproterenol-Induced Cardiomyocytes Apoptosis In Vitro and In Vivo
Morphologic changes in H9c2 cells and in LV tissues of rats. H9c2 cells were stained with Hoechst 33258 and the sections of LV tissue were stained with TUNEL. They were visualized under fluorescence or light microscope (magnifications: ×400). (a) Control cells; (b) ISO-treated H9c2 cells; (c) H89-treated H9c2 cells; (d) ISO+H89-treated H9c2 cells; (e) ISO+Rb1-treated H9c2 cells; (f) ISO+Rb1+H89-treated H9c2 cells; (g) control LV tissues in rat; (h) ISO-treated LV tissues in rat; (i) ISO+Rb1-treated LV tissues in rat. Arrows indicate apoptotic cells.
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