Research Article

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin

Figure 5

Regulation of network imbalance as an important therapeutic principle of herbal formula. Mutation/amplification and aberrant signal transduction cause the multiple changes of the normal network structure, leading to the imbalance of health state. Combinations of herbs used in herbal formula (substantially certain chemical compounds) can weakly target different proteins within the disease-specific network so as to restore the imbalanced disease state.
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