Effect of Formononetin on Mechanical Properties and Chemical Composition of Bones in Rats with Ovariectomy-Induced Osteoporosis

Table 1

Effects of estradiol and formononetin on the body mass gain and mass of organs in ovariectomized rats.

Parameters	SHAM	OVX	OVX + ES	OVX + FRM
Final body mass (g)	263.3 ± 10.5	272.6 ± 3.6	252.9 ± 7.2^B	270.0 ± 2.4
Body mass gain after 4 weeks (g)	32.1 ± 2.9	50.6 ± 3.8^AA	34.1 ± 4.5^B	49.8 ± 2.2
Uterus mass (g)	0.39 ± 0.01	0.09 ± 0.01^AAA	0.18 ± 0.01^BBB	0.09 ± 0.01
Thymus mass (g)	0.39 ± 0.04	0.68 ± 0.03^AAA	0.62 ± 0.05	0.72 ± 0.03

Results are presented as means ± SEM (𝑛=7). ^AA𝑃<0.01,^AAA𝑃<0.001—statistically significant differences between the OVX and the SHAM groups; ^B𝑃<0.05, ^BBB𝑃<0.001—statistically significant differences in comparison with the OVX group.