Curcumin Protects Neuron against Cerebral Ischemia-Induced Inflammation through Improving PPAR-Gamma Function

Figure 6

Cerebral ischemic injury was mediated by NF-κB. Rats were injected (i.p.) with curcumin and GW9662 for continuous 3 days. One hour after the last injections, the rats were subjected to MCAO for 2 h and reperfused for 24 h. (a) ELISA assay of IL-1β. (b) ELISA assay of TNF-α. Data were expressed as mean ± SD with 6 individual rats per group. *𝑃<0.05, **𝑃<0.01 versus sham-operated rats, and ^##𝑃<0.01 versus MCAO rats.

(a)

(b)