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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 503521, 13 pages
http://dx.doi.org/10.1155/2013/503521
Research Article

6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling

1Department of Cardiology, Shanghai East Hospital, Tongji University School of Medicine, 150 Jimo Road, Shanghai 200120, China
2Department of Oncology, Shanghai Shidong Hospital, Shanghai 200438, China
3Department of Emergency, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China
4Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
5Department of Pathology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA

Received 19 November 2012; Accepted 14 January 2013

Academic Editor: Muhammad Nabeel Ghayur

Copyright © 2013 Yun kai Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Jun-xia Jiang, Shui-juan Zhang, Ya-nan Liu, Xi-xi Lin, Yan-hong Sun, Hui-juan Shen, Xiao-feng Yan, and Qiang-min Xie, “EETs alleviate ox-LDL-induced inflammation by inhibiting LOX-1 receptor expression in rat pulmonary arterial endothelial cells,” European Journal of Pharmacology, vol. 727, pp. 43–51, 2014. View at Publisher · View at Google Scholar
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  • Laura Toma, Mina Raileanu, Mariana Deleanu, Camelia S. Stancu, and Anca V. Sima, “Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression,” Journal of Functional Foods, vol. 48, pp. 654–664, 2018. View at Publisher · View at Google Scholar
  • Yun Xu, Liwei Bai, Xuehui Chen, Yan Li, Yan Qin, Xiangyu Meng, and Qinggui Zhang, “6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity in db/db mice,” Biomedicine & Pharmacotherapy, vol. 97, pp. 633–641, 2018. View at Publisher · View at Google Scholar
  • Xingran Kou, Xiaoqi Wang, Ruya Ji, Lang Liu, Yening Qiao, Zaixiang Lou, Chaoyang Ma, Shiming Li, Hongxin Wang, and Chi-Tang Ho, “Occurrence, biological activity and metabolism of 6-shogaol,” Food & Function, 2018. View at Publisher · View at Google Scholar