Metabolic Profiles Distinguish Non-Dampness-Phlegm and Dampness-Phlegm Patterns among Korean Patients with Acute Cerebral Infarction
Table 4
Identification and quantification of metabolites in human plasma using UHPLC-MS and electrospray ionization in positive-ion mode.
Retention time (min)
Common name
Formula of
Measured mass (m/z)
Theoretical mass (m/z)
Mass error (Da)
Non-DP
DP
16.55
LPC(14:0)
C22H47NO7P+
468.35
468.31
+0.04
21.87 ± 11.51a
22.95 ± 9.12
0.145
16.86
LPC(16:1 (9Z))
C24H49NO7P+
494.36
494.32
+0.04
58.80 ± 35.99
56.53 ± 27.33
0.671
17.08
LPC(22:6)
C30H51NO7P+
568.38
568.34
+0.04
75.58 ± 30.32
77.35 ± 37.30
0.961
17.12
LPC(20:4)
C28H51NO7P+
544.37
544.34
+0.03
104.65 ± 31.01
94.62 ± 33.85
0.070
17.15
LPC(18:2(9Z, 12Z))
C26H51NO7P+
520.36
520.34
+0.02
304.62 ± 48.29
282.22 ± 53.29
0.010
17.15
unknown
1063.75
45.49 ± 17.50
40.35 ± 17.42
0.058
17.46
LPC(20:3)
C28H53NO7P+
546.39
546.35
+0.04
41.14 ± 17.33
35.35 ± 14.02
0.034
17.51
LPC(16:0)
C24H51NO7P+
496.36
496.34
+0.02
530.37 ± 56.28
533.84 ± 64.59
0.583
17.69
LPC(18:1)
C26H53NO7P+
522.38
522.36
+0.02
261.34 ± 38.55
249.65 ± 39.38
0.077
18.21
LPC(18:0)
C26H55NO7P+
524.39
524.37
+0.02
398.11 ± 41.16
402.10 ± 52.47
0.391
19.10
Dioctyl phthalate (plasticizer contaminant)
391.31
391.28
+0.03
31.27 ± 5.95
31.27 ± 4.95
0.817
19.38
DG(40:4)
673.58
673.58
+0.007
32.77 ± 15.44
36.78 ± 19.95
0.306
19.67
DG(40:3)
675.58
675.59
-0.01
228.01 ± 38.68
229.73 ± 45.96
0.812
19.73
DG(42:4)
701.59
701.60
−0.01
289.45 ± 45.60
289.82 ± 44.59
0.961
19.85
PC(36:5)
C44H79NO8P+
780.59
780.55
+0.04
213.70 ± 45.71
224.66 ± 45.41
0.156
19.90
PC(34:3)
C42H79NO8P+
756.61
756.55
+0.06
57.74 ± 29.96
58.82 ± 28.32
0.840
19.95
PC(38:6)
C46H81NO8P+
806.61
806.56
+0.05
219.88 ± 37.58
228.46 ± 45.82
0.501
19.99
DG(42:3)
703.61
703.62
−0.01
172.78 ± 29.19
179.24 ± 41.33
0.564
20.00
Unknown
1485.24
63.66 ± 25.34
66.75 ± 23.35
0.536
20.01
PC(36:4)
C44H81NO8P+
782.62
782.57
+0.05
131.29 ± 18.25
128.28 ± 22.48
0.095
20.08
PC(38:5)
C46H83NO8P+
808.66
808.59
+0.07
30.93 ± 11.17
32.02 ± 13.12
0.760
20.09
PC(34:2)
C42H81NO8P+
758.60
758.57
+0.03
195.39 ± 23.93
197.90 ± 27.36
0.565
20.15
PC(36:3)
C44H83NO8P+
784.63
784.58
+0.045
135.50 ± 23.95
133.31 ± 23.26
0.300
20.30
PC(34:1)
C42H83NO8P+
760.63
760.58
+0.05
149.14 ± 26.43
154.41 ± 26.00
0.235
20.32
PC(38:4)
C46H85NO8P+
810.68
810.60
+0.08
49.85 ± 13.02
49.02 ± 13.32
0.638
20.37
PC(36:2)
C44H85NO8P+
786.64
786.60
+0.04
168.87 ± 19.57
170.71 ± 25.72
0.635
20.43
PC(38:3)
C46H87NO8P+
812.68
812.62
+0.06
60.73 ± 26.71
55.31 ± 22.62
0.149
20.78
SM(d18:1/24:1(15Z))
C47H94N2O6P+
813.73
813.68
+0.05
132.91 ± 52.04
131.24 ± 59.93
0.704
20.79
SM(d18:0/22:1(13Z))
C45H92N2O6P+
787.72
787.67
+0.05
50.88 ± 40.64
44.42 ± 39.20
0.217
Data are presented as mean ± SD. The value was calculated by Mann-Whitney test. LPC: lysophosphatidylcholine; PC: phosphatidylcholine; DG: diacylglycerol; SM: sphingomyelin.
