Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis
Figure 1
Intakes of fructose (a), laboratory chow (b), and energy (c), body weight (d), epididymal and perirenal white adipose tissue (e + p WAT) weight (e), and the ratio of e + p WAT weight to body weight (f) in water-control, 10% fructose solution-control and fructose pair-fed oleanolic acid- (OA-) treated rats. Animals were administered with OA (5 or 25 mg/kg/day) or vehicle (OA: 0 mg/kg, 5% Gum Arabic) by oral gavage daily for 10 weeks. Data are means ± SEM ( each group). .
