Metabolic Signatures of Kidney Yang Deficiency Syndrome and Protective Effects of Two Herbal Extracts in Rats Using GC/TOF MS

Table 1

Hormone variation and behavioral investigation results on the 3rd day after hydrocortisone withdrawal with or without WKY1/WKY2 pretreatments.

Groups	Cortisone; (ng/mL)	ACTH; (pg/mL)	17-OHCS; (μmol/L)	Body weight (g)	Food consumption (g)	Water intake (mL)	Urine volume (mL)
Control group	220.78 ± 105.78	633.43 ± 111.1	433.81 ± 15.64	371.9 ± 7.2	14.8 ± 1.3	48.9 ± 4.3	40.6 ± 5.9
Model group	139.21 ± 40.79**	447.14 ± 126.5*	398.91 ± 29.13**	349.0 ± 12.0**	13.4 ± 1.1	36.3 ± 4.5**	18.4 ± 6.0**
WKY1 group	161.84 ± 87.27	632.98 ± 50.65	400.6 ± 16.59	356.6 ± 15.6*	15.1 ± 2.5	42.3 ± 5.9*	27.9 ± 8.4**
WKY2 group	206.51 ± 71.64	993.26 ± 17.46**	416.79 ± 12.78	357.4 ± 12.4*	14.9 ± 2.1	34.8 ± 4.6**	20.4 ± 2.8**

^∗𝑃<0.05, ^∗∗𝑃<0.01 compared with control group (two-tailed Student’s 𝑡-test).