Clinical Study on the Prevention of Oxaliplatin-Induced Neurotoxicity with Guilongtongluofang: Results of a Randomized, Double-Blind, Placebo-Controlled Trial

Table 2

Incidence of oxaliplatin-induced neurotoxicity in the trial group and the control group.

Neurotoxicity	Trial group (𝑛, %); (𝑛=60)	Control group (𝑛, %); (𝑛=60)	𝑃 value
After two cycles
Grade 0	52 (86.7)	48 (80.0)	0.04
Grades 1-2	8 (13.3)	11 (18.3)
Grades 3-4	0 (0.0)	1 (1.7)
After four cycles
Grade 0	43 (71.7)	34 (56.7)	0.05
Grades 1-2	14 (23.3)	18 (30.0)
Grades 3-4	3 (5.0)	8 (13.3)
After six cycles
Grade 0	29 (48.3)	18 (30.0)	0.04
Grades 1-2	24 (40.0)	23 (38.3)
Grades 3-4	7 (11.7)	19 (31.7)