Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 542081, 6 pages
http://dx.doi.org/10.1155/2013/542081
Research Article

The Neuroprotective Effect of Gugijihwang-Tang on Trimethyltin-Induced Memory Dysfunction in the Rat

1Department of Basic Korean Medical Science, Acupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 130-701, Republic of Korea
2Hospital of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea
3Department of Basic Oriental Medical Science, College of Oriental Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea

Received 21 November 2012; Revised 8 April 2013; Accepted 15 May 2013

Academic Editor: Rong Zeng

Copyright © 2013 Eun-Yee Jung et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Di Carlo, D. Giacomazza, and P. L. San Biagio, “Alzheimer's disease: biological aspects, therapeutic perspectives and diagnostic tools,” Journal of Physics, vol. 24, no. 24, Article ID 244102, 2012. View at Google Scholar
  2. L. W. Chang and R. S. Dyer, “A time-course study of trimethyltin induced neuropathology in rats,” Neurobehavioral Toxicology and Teratology, vol. 5, no. 4, pp. 443–459, 1983. View at Google Scholar · View at Scopus
  3. T. W. Bouldin, N. D. Goines, C. R. Bagnell, and M. R. Krigman, “Pathogenesis of trimethyltin neuronal toxicity,” American Journal of Pathology, vol. 104, no. 3, pp. 237–249, 1981. View at Google Scholar · View at Scopus
  4. D. G. Robertson, R. H. Gray, and F. A. De la Iglesia, “Quantitative assessment of trimethyltin induced pathology of the hippocampus,” Toxicologic Pathology, vol. 15, no. 1, pp. 7–17, 1987. View at Google Scholar · View at Scopus
  5. N. Ishida, M. Akaike, S. Tsutsumi et al., “Trimethyltin syndrome as a hippocampal degeneration model: temporal changes and neurochemical features of seizure susceptibility and learning impairment,” Neuroscience, vol. 81, no. 4, pp. 1183–1191, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. R. S. Dyer, T. J. Walsh, W. F. Wonderlin, and M. Bercegeay, “The trimethyltin syndrome in rats,” Neurobehavioral Toxicology and Teratology, vol. 4, no. 2, pp. 127–133, 1982. View at Google Scholar · View at Scopus
  7. P. H. Ruppert, T. J. Walsh, L. W. Reiter, and R. S. Dyer, “Trimethyltin-induced hyperactivity: time course and pattern,” Neurobehavioral Toxicology and Teratology, vol. 4, no. 2, pp. 135–139, 1982. View at Google Scholar · View at Scopus
  8. Y. Liu, H. Imai, M. Sadamatsu, K. Tsunashima, and N. Kato, “Cytokines participate in neuronal death induced by trimethyltin in the rat hippocampus via type II glucocorticoid receptors,” Neuroscience Research, vol. 51, no. 3, pp. 319–327, 2005. View at Google Scholar · View at Scopus
  9. V. Corvino, E. Marchese, F. Michetti, and M. C. Geloso, “Neuroprotective strategies in hippocampal neurodegeneration induced by the neurotoxicant trimethyltin,” Neurochemical Research, vol. 38, no. 2, pp. 240–253, 2013. View at Google Scholar
  10. M. C. Geloso, V. Corvino, and F. Michetti, “Trimethyltin-induced hippocampal degeneration as a tool to investigate neurodegenerative processes,” Neurochemistry International, vol. 58, no. 7, pp. 729–738, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Birks, E. V. Grimley, and M. Van Dongen, “Ginkgo biloba for cognitive impairment and dementia,” Cochrane Database of Systematic Reviews, no. 4, Article ID CD003120, 2002. View at Google Scholar · View at Scopus
  12. D. O. Kennedy, A. B. Scholey, L. Drewery, V. R. Marsh, B. Moore, and H. Ashton, “Electroencephalograph effects of single doses of Ginkgo biloba and Panax ginseng in healthy young volunteers,” Pharmacology Biochemistry and Behavior, vol. 75, no. 3, pp. 701–709, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Rho, M. Kang, B. Choi et al., “Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus,” Biological and Pharmaceutical Bulletin, vol. 28, no. 1, pp. 87–93, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. E. Park, M. Kang, J. Oh et al., “Yukmijihwang-tang derivatives enhance cognitive processing in normal young adults: a double-blinded, placebo-controlled trial,” American Journal of Chinese Medicine, vol. 33, no. 1, pp. 107–115, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. M. Mirrione, W. K. Schiffer, M. Siddiq, S. L. Dewey, and S. E. Tsirka, “PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy,” Synapse, vol. 59, no. 2, pp. 119–121, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. M. M. Mirrione, W. K. Schiffer, J. S. Fowler, D. L. Alexoff, S. L. Dewey, and S. E. Tsirka, “A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator,” NeuroImage, vol. 38, no. 1, pp. 34–42, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Lee, D. Son, P. Lee et al., “Protective effect of methanol extract of Uncaria rhynchophylla against excitotoxicity induced by N-methyl-D-aspartate in rat hippocampus,” Journal Pharmacological Sciences, vol. 92, no. 1, pp. 70–73, 2003. View at Google Scholar · View at Scopus
  18. H. S. Swartzwelder, R. S. Dyer, W. Holahan, and R. D. Myers, “Activity changes in rats following acute trimethyltin exposure,” NeuroToxicology, vol. 2, no. 3, pp. 589–593, 1981. View at Google Scholar · View at Scopus
  19. B. Earley, M. Burke, and B. E. Leonard, “Behavioural, biochemical and histological effects of trimethyltin (TMT) induced brain damage in the rat,” Neurochemistry International, vol. 21, no. 3, pp. 351–366, 1992. View at Publisher · View at Google Scholar · View at Scopus
  20. L. P. Lanier and R. L. Isaacson, “Activity changes related to the location of lesions in the hippocampus,” Behavioral Biology, vol. 13, no. 1, pp. 59–69, 1975. View at Google Scholar · View at Scopus
  21. J. A. Luchsinger, J. M. Noble, and N. Scarmeas, “Diet and Alzheimer's disease,” Current Neurology and Neuroscience Reports, vol. 7, no. 5, pp. 366–372, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Toro, P. Schönknecht, and J. Schröder, “Type II diabetes in mild cognitive impairment and Alzheimer's disease: results from a prospective population-based study in Germany,” Journal of Alzheimer's Disease, vol. 16, no. 4, pp. 687–691, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. R. A. Sperling, B. C. Dickerson, M. Pihlajamaki et al., “Functional alterations in memory networks in early alzheimer's disease,” NeuroMolecular Medicine, vol. 12, no. 1, pp. 27–43, 2010. View at Publisher · View at Google Scholar · View at Scopus