Effect of KIOM-79 on Diabetes-Induced Myocardial Fibrosis in Zucker Diabetic Fatty Rats
Effect of KIOM-79 on cardiac interstitial fibrosis. (a) Representative images for Masson’s trichrome staining in the heart of ZL rats (A), untreated ZDF rats (B), ZDF rats treated with KIOM-79 (50 mg/kg) (C) and ZDF rats treated with KIOM-79 (500 mg/kg) (D). Positive staining is visible in blue. Original magnification: ×200. (b) Quantitative analysis. The positive stained area was calculated. All data were expressed as the mean ± S.E.M. * compared to ZL rats; # compared to untreated ZDF rats.
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