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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 569737, 8 pages
Research Article

Medicinal Fungus Antrodia cinnamomea Inhibits Growth and Cancer Stem Cell Characteristics of Hepatocellular Carcinoma

1Cancer Center, Taipei Veterans General Hospital, Taipei 11217, Taiwan
2Institute of Traditional Medicine, School of Medicine, National Yang Ming University, Taipei 11221, Taiwan
3Department of Chemical and Material Engineering, Chang Gung University, Kwei-Shan, Tao-Yuan 333, Taiwan
4Department of Education and Research, Taipei City Hospital, Taipei 10341, Taiwan
5Department of Radiation Oncology, Mackay Memorial Hospital, Taipei 10449, Taiwan

Received 1 January 2013; Accepted 16 January 2013

Academic Editor: Hui-Fen Liao

Copyright © 2013 Yu-Ming Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Yen-Ju Chen, Mike W. C. Thang, Yu-Tzu Chan, Yu-Feng Huang, Nianhan Ma, Alice L. Yu, Chung-Yi Wu, Miao-Lin Hu, and Kuo Ping Chiu, “Global Assessment of Antrodia cinnamomea-Induced MicroRNA Alterations in Hepatocarcinoma Cells,” Plos One, vol. 8, no. 12, 2013. View at Publisher · View at Google Scholar
  • Ming-Jyh Sheu, Yu-Ning Teng, Ying-Yi Chen, and Chin-Chuan Hung, “The Functional Influences of Common ABCB1 Genetic Variants on the Inhibition of P-glycoprotein by Antrodia cinnamomea Extracts,” Plos One, vol. 9, no. 2, 2014. View at Publisher · View at Google Scholar
  • Chiao-I. Lai, Yung-Lin Chu, Chi-Tang Ho, Yu-Cheng Su, Yueh-Hsiung Kuo, and Lee-Yan Sheen, “Antcin K, an active triterpenoid from the fruiting bodies of basswood cultivated Antrodia cinnamomea, induces mitochondria and endoplasmic reticulum stress-mediated apoptosis in human hepatoma cells,” Journal of Traditional and Complementary Medicine, 2015. View at Publisher · View at Google Scholar
  • Tse-Hung Huang, Kuang-Hung Hsu, Chang-Jer Wu, Yi-Han Chiu, Yi-Lin Chan, Wang Wang, Tsung-Lin Li, Chien-Yin Liu, Cheng-Ta Yang, Tzung-Yan Lee, and Jyh-Sheng You, “Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice,” Oncotarget, vol. 6, no. 28, pp. 25741–25754, 2015. View at Publisher · View at Google Scholar
  • Yu-Kuo Liu, Kuan-Hsing Chen, Yann-Lii Leu, Tzong-Der Way, Ling-Wei Wang, Yu-Jen Chen, and Yu-Ming Liu, “Ethanol extracts of Cinnamomum kanehirai Hayata leaves induce apoptosis in human hepatoma cell through caspase-3 cascade,” Oncotargets And Therapy, vol. 8, pp. 99–108, 2015. View at Publisher · View at Google Scholar
  • Ming Hong, Hor Tan, Sha Li, Fan Cheung, Ning Wang, Tadashi Nagamatsu, and Yibin Feng, “Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds,” International Journal of Molecular Sciences, vol. 17, no. 6, pp. 893, 2016. View at Publisher · View at Google Scholar
  • Yu-Kuo Liu, Ling-Wei Wang, Yu-Chuen Huang, Pin Ihuang, Tung-Hu Tsai, Yu-Ming Liu, and Yu-Jen Chen, “The medicinal fungus Antrodia cinnamomea regulates DNA repair and enhances the radiosensitivity of human esophageal cancer cells,” OncoTargets and Therapy, vol. 9, pp. 6651–6661, 2016. View at Publisher · View at Google Scholar
  • Zhaokun Yan, Zijun Lai, and Jiumao Lin, “Anticancer properties of traditional Chinese medicine,” Combinatorial Chemistry and High Throughput Screening, vol. 20, no. 5, pp. 423–429, 2017. View at Publisher · View at Google Scholar
  • Yulin Zhou, Qingfan Meng, Ning Wang, Qiming Liang, Jing Xie, Zhihua Guo, Jiahui Lu, Hui Liu, Yutong Quan, and Di Wang, “Cordycepin affects multiple apoptotic pathways to mediate hepatocellular carcinoma cell death,” Anti-Cancer Agents in Medicinal Chemistry, vol. 17, no. 1, pp. 143–149, 2017. View at Publisher · View at Google Scholar
  • Yu-Kuo Liu, Yu-Ming Liu, Pin-I. Huang, Tung-Hu Tsai, and Yu-Jen Chen, “Antrodia cinnamomea mycelial fermentation broth inhibits the epithelial-mesenchymal transition of human esophageal adenocarcinoma cancer cells,” Food and Chemical Toxicology, vol. 119, pp. 380–386, 2018. View at Publisher · View at Google Scholar