Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study

Table 2

Semen profile of the Ashwagandha root extract-treated and placebo-treated oligospermic males.

	Placebo-treated group (𝑛=25)			Ashwagandha-treated group (𝑛=21)
	Day 0	Day 60	Day 90	Day 0	Day 60	Day 90
Sperm concentration (×10^6/mL)	10.24±2.82	12.42±4.75	13.23±7.74	9.59±4.37	18.8±5.7^#	25.61±8.6^#
Semen volume (mL)	1.88±0.65	2.3±0.58	2.25±0.41	1.74±0.58	2.56±0.7^∗	2.76±0.6^#
Sperm motility (%)	18.6±5.41	18.87±5.86	20.27±5.97	18.62±6.11	26.04±5.6^#	29.19±6.31^#
Serum testosterone ng/mL	4.42±1.50	—	4.59±1.48	4.45±1.41	—	5.22±1.39
Serum LH mIU/mL	4.02±1.20	—	4.35±1.28	3.97±1.21	—	5.31±1.33

^∗𝑃<0.05, ^#𝑃<0.0001 as compared to the baseline values on Day 0 of the study duration (12 weeks). Values are expressed as mean ± SD.