Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug
Figure 5
Pathway activities altered by EEDS treatment in A549 cells. (a) The dose-dependent change in pathway activities was measured and clustered hierarchically. Columns represent individual samples, and rows represent activities of pathways. The pathway activity color scale ranges from red (high) to green (low), as indicated by scale bars with arbitrary units. The pathway positions are colored green to indicate metabolic pathways and red to indicate signaling-related pathways. (b) After measurement of the similarity between pathways, the matrix of similarity was clustered hierarchically and merged with activities of pathways. The level of similarity is represented in red with a scale bar. The color in the box of a diagonal line or “Activity” on the right panel represents the activity of the pathway. The positions of signaling-related pathways are colored red and the metabolism-related pathways are colored blue.
