Gene Expression Profile of the A549 Human Non-Small Cell Lung Carcinoma Cell Line following Treatment with the Seeds of Descurainia sophia, a Potential Anticancer Drug

Table 5

Pathways associated with Up- and Down-patterns by EEDS treatment.

KEGG ID	Pathway	𝑃 value*	FDR**
Down-pattern
03410	Base excision repair	3.90𝐸−04	6.66𝐸−03
00030	Pentose phosphate pathway	1.47𝐸−04	1.22𝐸−03
Up-pattern
04010	MAPK signaling pathway	1.16𝐸−07	1.83𝐸−05
04210	Apoptosis	4.99𝐸−06	3.94𝐸−04
04115	p53 signaling pathway	2.46𝐸−05	1.29𝐸−03
04350	TGF-beta signaling pathway	5.36𝐸−05	2.11𝐸−03
04060	Cytokine-cytokine receptor interaction	1.14𝐸−04	3.60𝐸−03
04710	Circadian rhythm	3.20𝐸−04	8.38𝐸−03
04621	NOD-like receptor signaling pathway	3.39𝐸−04	7.61𝐸−03

^∗𝑃 values were calculated using Fischer’s test.
∗∗FDR corrections were calculated using the Benjamini-Hochberg procedure [17].